4th – 5th December 2023, Novotel Schiphol Airport, Amsterdam

Welcome to GBR’s PharmaWorX

Pharma Innovation, PharmaWorX – A GBR Community Meeting is taking place in Amsterdam, The Netherlands. This closed-door gathering of senior executives is a truly unparalleled opportunity to share meaningful and honest dialogue in a media-free environment.
Participants
GBR Community Includes

and many more..

Join as Participant

Partners
PharmaWorX 2023 Partners include

and many more..

Become a Partner

Speakers

PharmaWorX Speakers include

Dr. Ingo Muckenschnabel

Dr. Ingo Muckenschnabel

Senior Manager, Scientific Operations

Kyle Tansill

Kyle Tansill

Digital Manufacturing Solutions Architect

Dr. Trixie Wagner

Dr. Trixie Wagner

Lead GDC Lab Informatics & Lab Automation

Michael Peter Langner

Michael Peter Langner

Group Lead Process Analysis & Transfer

and many more..

GBR Community

Agenda

PharmaWorX – Accelerating Transformation of Life Science, Pharma and Biotech R&D with Automation, AI/ML & Robotics Tools

DAY 1 – 4th DECEMBER 2023

AUTOMATION WITH AI/ML & ROBOTICS TOOLS IN DRUG DISCOVERY & DEVELOPMENT

  • Lab robotics & tools for drug discovery workflows:
    – Automated liquid handlers
    – Microplate readers
    – Data visualisation tools

  • Implementing AI/ML in the lab
  • Robotic process automation
  • Maximizing R&D through cloud-based control and automation of scientific workflows

DIGITAL STRATEGIES TO POWER NEXT-GENERATION BIOPHARMA

  • How to build the right foundation to ensure confidence in the accuracy and availability of your data
  • Understand how to get actionable insights that address roadblocks before they happen and
  • Discover how digital workflows can speed time-to-insight with advanced data analytics and visualization tools

VISION FOR FUTURE AND SCOPE OF THE MOBILE ROBOTICS IN DRUG DEVELOPMENT

  • Overcoming challenges: what is missing?
    – What new technologies are needed?
    – What constitute industry proof of concept?
  • Industry expectations to achieve the biggest impact?
  • Return on investment – benchmarking

SUSTAINABILITY AND THE LAB OF THE FUTURE – LOWERING CARBON FOOTPRINT

  • Sustainability innovations, including oil free vacuum pumps, reduced footprint instruments, and column technologies that reduce solvent requirements and hazardous waste
  • Fully digitized lab to reduce the requirement for paper
  • Miniaturization, lab space, smaller instruments utilising less material and disposal and reduced power requirements
  • Smaller samples requiring less reagent use too – both in terms of sample preparation and downstream waste

DIGITALISATION IN QA/QC LABS

  • Building a digital and cost-effective QA/QC lab
  • Accelerating digital transformation and developing and adopting a smart infrastructure
  • Adoption of digital tools & technologies in QA/QC labs

Smart Lab Ecosystem – Connecting the digital & real world for a highly adaptable, safe & sustainable research

  • Research spaces and laboratories are facing many challenges and undergoing fundamental transformation
  • The complexity of the laboratory infrastructure requires numerous, involved disciplines and yesterday’s concepts cannot meet future requirements
  • A fundamentally new approach is required to address the challenges, to foster the innovation and remain competitive
  • Smart Lab Ecosystem approach combines real and digital world to manage and reduce complexity
  • The talk will outline our vision what a lab of the future looks like and why we think it’s (r)evolutionary

Laboratories in Transformation

  • Recent big topics affecting today’s laboratories
  • How to engage employees and promote acceptance for digitization and automation
  • User Experience and User Centric Design
  • Benefits from User Centric Solutions and their ROI

TOWARDS ROBOTIC LABORATORY AUTOMATION PLUG & PLAY

  • Laboratory automation robotics landscape
  • Use-cases
  • Challenges
  • Standardization
  • Plug & play integration
  • Research areas

AUTOMATION & PROCESS OPTIMISATION IN QA/QC LABS

  • Maximising system’s efficiency in the lab:
  • Developing software & hardware for automated systems
  • Lab analysis methods
  • Cloud-based systems
  • Integrating different lab systems
  • Optimisation of lab processes – use cases

ACCELERATING PRECISION MEDICINE – TURNING DATA INTO INSIGHTS USING AI AND AUTOMATION

  • Life sciences is being transformed through embracing technology advancements that leverage cloud computing, instrument connectivity, and the power of data to drive innovation
  • Our research shows that leaders in the precision medicine space, are embracing change to adopt these emerging best practices to yield quicker results
  • We will breakdown the complexities for researchers, scientists, and technologist into four components: 1/Data Management, 2/Industry Regulations, 3/Cloud
  • Elasticity, and 4/How Artificial Intelligence (AI) is being used to accelerate precision medicine

ACCELERATING BIOPHARMA DISCOVERY PROCESSES WITH AUTOMATION

  • Modernising and embedding automation to increase screening capacity and remove time consuming make-test cycles
  • Automating sample preparation, assay miniaturization & improved data management strategies
  • Creating a data-rich environment enabling selection of high-quality leads, acceleration of cycle times to candidate and reduction of time on manual tasks freeing up FTEs to focus on science

ADDRESSING WORKFORCE CHALLENGES IN PHARMACEUTICALS WITH AUGMENTED REALITY

  • Accelerate learning and reduces training costs
  • Improve accuracy
  • Decrease the costs of human error, scrap, and waste
  • Improve adherence to safety and compliance regulations

DAY 2 – 5th DECEMBER 2023

LAB SUSTAINABILITY AND DIGITALIZATION

  • Reduce their carbon footprint and minimize their waste
  • Maintaining regulatory obligations whilst reducing energy use and increasing efficiency
  • Improve efficiency and sustainability through lab digitalization facilitating operations management, waste reduction, and optimized use of lab equipment, real-time insights on operational inefficiencies
  • Utilising data to make changes that reduce waste, save time, lower costs, and improve efficiency

CONNECTING & DIGITIZING YOUR ENTIRE LAB ENVIRONMENT

  • Improving efficiency and optimizing workflows
  • Benefits & challenges of digital tools, Data management, Digital security
  • The importance of lab culture for the adoption of digital tools

IMPLEMENTING AUTOMATION IN THE GLOBAL R&D STRATEGY

  • How is the automation strategy aligning with the digital strategy to support structured data and a cohesive flow from experiment design through to assessment?
  • Examples of creating an automation culture end-to-end: How the Smart Lab of the future fuels scientific development and minimizes human intervention, creating more room in the researcher’s timetable for innovation and improved methods of conducting experiments

LAB 4.0: MAKING DIGITAL TRANSFORMATION WORK FOR YOUR LABORATORY

  • The laboratory of the future is a connected, automated environment that enables scientists to quickly engage with equipment, data and collaborators wherever they are
  • To progress towards digital maturity and realize the productivity and quality gains promised by Lab 4.0, a critical first step is connectivity
  • Key to achieving this connectivity is to implement a LIMS that integrates organizational and laboratory systems and instrumentation, regardless of manufacturer or technique, to improve data quality and preserve data integrity
  • This will allow your organization to benefit from maximum automation, advanced analytical technologies and a highly skilled globally distributed workforce

HOW SOFTWARE CAN DRIVE YOUR LAB TO A SUSTAINABLE FUTURE

  • Reducing your lab’s carbon footprint can save on costs
  • Savings can be had from unexpected places, including temperature control and storage optimization
  • Cloud technology encourages proper data management and ensures processes are streamlined

DIGITAL TECHNOLOGY-BASED CAPABILITIES FOR THE QC LAB OF THE FUTURE

  • Systems interoperability and governance
  • Data analytics and infrastructure
  • IT security and operations
  • Lab enablement
  • People and culture

MODERNIZATION IS KEY: LEVERAGING INNOVATIVE LABORATORY SOLUTIONS TO DRIVE DIGITAL TRANSFORMATION

  • Enhancing Data security, Scalability, Flexibility, Governance and Compliance
  • Integration with Cloud Technologies

THE FUTURE OF AI ENABLED DRUG DISCOVERY

  • In this presentation we will discuss the importance of rapid design cycles and how virtuous learning loops are critical to driving projects forward
  • Automated synthesis and screening will play a pivotal role in the next leap forward in speed and productivity and we will discuss our progress in this area and how AI design is critical to the implementation of automated, digital laboratories

ARTIFICIAL INTELLIGENCE AND AUTOMATION ENABLING RAPID, WIDELY AVAILABLE AUTOLOGOUS CAR-T CELL THERAPY

  • This talk will elaborate on the translation of manual CAR-T cell manufacturing and quality control to an automated system with a focus on adaptability to the changing needs of the industry

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